KMID : 0359720080260010073
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Journal of the Korean Neurological Association 2008 Volume.26 No. 1 p.73 ~ p.77
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Pisa Syndrome in a Patient with Alzheimer¡¯s Disease and Concomitant Normal Pressure Hydrocephalus: A Case Report
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Kwon Oh-Dae
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Abstract
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Extrapyramidal symptoms are common in patients with advanced Alzheimer¡¯s disease and have various etiologies. We report a 65-year-old man with probable Alzheimer¡¯s disease (AD) who concomitantly developed Pisa syndrome, ataxic gait, postural instability and voiding difficulty. Pisa syndrome improved after the discontinuation of acetylcholinesterase inhibitor (AchEI) and antipsychotics. However his ataxic gait and voiding symptoms persisted. A ventriculo-peritoneal shunt operation eliminated the symptoms except for cognition. We report Pisa syndrome in a patient with Alzheimer¡¯s disease and concomitant normal pressure hydrocephalus.
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KEYWORD
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Alzheimer disease, Normal pressure hydrocephalus, Pisa syndrome
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